ADD1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | P35611 |
Other Accession | Q5RA10 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 80955 Da |
Gene ID | 118 |
---|---|
Other Names | Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA |
Target/Specificity | This ADD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 428-462 amino acids from the Central region of human ADD1. |
Dilution | WB~~1:2000 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADD1 |
---|---|
Synonyms | ADDA |
Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
Cellular Location | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Tissue Location | Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit |
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Provided below are standard protocols that you may find useful for product applications.
Background
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
References
Joshi R.L.,et al.J. Cell Biol. 115:665-675(1991).
Goldberg Y.P.,et al.Hum. Mol. Genet. 1:669-675(1992).
Lin B.,et al.Genomics 25:93-99(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
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