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CLEC1B Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - CLEC1B Antibody (N-Term) AP22306a
    All lanes : Anti-CLEC1B Antibody (N-Term) at dilution Lane 1: HepG2 whole cell lysate Lane 2: U266B1 whole cell lysate Lane 3: 293 whole cell lysate Lane 4: Human testis lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9P126
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 26596 Da
Additional Information
Gene ID 51266
Other Names C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2, CLEC1B, CLEC2
Target/Specificity This CLEC1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-78 amino acids from the human region of human CLEC1B.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC1B Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC1B
Synonyms CLEC2
Function C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN (PubMed:18215137). After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 (PubMed:18955485).
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
Research Areas
Citations (0)
citation

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References

Colonna M.,et al.Eur. J. Immunol. 30:697-704(2000).
Chaipan C.,et al.J. Virol. 80:8951-8960(2006).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Scherer S.E.,et al.Nature 440:346-351(2006).
Suzuki-Inoue K.,et al.Blood 107:542-549(2006).

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$ 365.00
$ 140.00
Cat# AP22306a
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