CLEC1B Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9P126 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26596 Da |
Gene ID | 51266 |
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Other Names | C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2, CLEC1B, CLEC2 |
Target/Specificity | This CLEC1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-78 amino acids from the human region of human CLEC1B. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CLEC1B Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CLEC1B |
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Synonyms | CLEC2 |
Function | C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN (PubMed:18215137). After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2 (PubMed:18955485). |
Cellular Location | Membrane; Single-pass type II membrane protein |
Tissue Location | Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. |
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Provided below are standard protocols that you may find useful for product applications.
References
Colonna M.,et al.Eur. J. Immunol. 30:697-704(2000).
Chaipan C.,et al.J. Virol. 80:8951-8960(2006).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Scherer S.E.,et al.Nature 440:346-351(2006).
Suzuki-Inoue K.,et al.Blood 107:542-549(2006).
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