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SH3PXD2B Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - SH3PXD2B Antibody (Center) AP22209c
    All lanes : Anti-SH3PXD2B Antibody (Center) at 1:2000 dilution Lane 1: U-251 MG whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lane 3: U-87 MG whole cell lysate Lane 4: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 102 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession A1X283
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 101579 Da
Antigen Region 505-539 aa
Additional Information
Gene ID 285590
Target/Specificity This SH3PXD2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the Central region of human SH3PXD2B.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSH3PXD2B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH3PXD2B
Synonyms FAD49, KIAA1295, TKS4
Function Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation (By similarity).
Cellular Location Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells.
Tissue Location Expressed in fibroblasts.
Research Areas
Citations (0)
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$ 365.00
$ 140.00
Cat# AP22209c
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