RPS2 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
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Primary Accession | P15880 |
Other Accession | O18789, P46791, Q90YS3, P25444, P27952, G1SWM1 |
Reactivity | Human, Mouse |
Predicted | Bovine, Hamster, Rabbit, Rat |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 31324 Da |
Gene ID | 6187 |
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Other Names | 40S ribosomal protein S2, 40S ribosomal protein S4, Protein LLRep3, RPS2, RPS4 |
Target/Specificity | This RPS2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 45-79 amino acids from human RPS2. |
Dilution | WB~~1:2000 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RPS2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RPS2 |
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Synonyms | RPS4 |
Function | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:23636399). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:23636399). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:23636399). Plays a role in the assembly and function of the 40S ribosomal subunit (By similarity). Mutations in this protein affects the control of translational fidelity (By similarity). Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). |
Cellular Location | Cytoplasm. Nucleus, nucleolus. Note=Probably localized to nucleolus and cytoplasm in complex with ZNF277. |
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Provided below are standard protocols that you may find useful for product applications.
References
Slynn G.,et al.Nucleic Acids Res. 18:681-681(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Vladimirov S.N.,et al.Eur. J. Biochem. 239:144-149(1996).
Swiercz R.,et al.Biochem. J. 386:85-91(2005).
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