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SRD5A1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P18405 |
| Other Accession | Q28891 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29459 Da |
| Gene ID | 6715 |
|---|---|
| Other Names | 3-oxo-5-alpha-steroid 4-dehydrogenase 1, 1.3.1.22, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1, SRD5A1 |
| Target/Specificity | This SRD5A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 153-184 amino acids from the Central region of human SRD5A1. |
| Dilution | WB~~1:8000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SRD5A1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SRD5A1 (HGNC:11284) |
|---|---|
| Function | Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. |
| Cellular Location | Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Liver and prostate (at a low level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
References
Andersson S.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:3640-3644(1990).
Jenkins E.P.,et al.Genomics 11:1102-1112(1991).
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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