CTBS Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q01459 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 43760 Da |
Gene ID | 1486 |
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Other Names | Di-N-acetylchitobiase, 3.2.1.-, CTBS, CTB |
Target/Specificity | This CTBS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 141-172 amino acids from the Central region of human CTBS. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CTBS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CTBS |
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Synonyms | CTB |
Function | Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase. |
Cellular Location | Lysosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.
References
Fisher K.J.,et al.J. Biol. Chem. 267:19607-19616(1992).
Liu B.,et al.Glycobiology 9:589-593(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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