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ARF4 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P18085 |
| Other Accession | Q5RCF1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20511 Da |
| Gene ID | 378 |
|---|---|
| Other Names | ADP-ribosylation factor 4, ARF4, ARF2 |
| Target/Specificity | This ARF4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 72-106 amino acids from the Central region of human ARF4. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ARF4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ARF4 |
|---|---|
| Synonyms | ARF2 |
| Function | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation (PubMed:25673879). |
| Cellular Location | Golgi apparatus. Membrane; Lipid-anchor |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
References
Monaco L.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:2206-2210(1990).
Kahn R.A.,et al.J. Biol. Chem. 266:2606-2614(1991).
Lebeda R.A.,et al.Gene 237:209-214(1999).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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