SLC2A3 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
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Primary Accession | P11169 |
Other Accession | Q8TDB8, Q5R608, Q9XSC2 |
Reactivity | Human, Mouse, Rat |
Predicted | Rabbit |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 53924 Da |
Antigen Region | 432-463 aa |
Gene ID | 6515 |
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Other Names | Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3, SLC2A3, GLUT3 |
Target/Specificity | This SLC2A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 432-463 amino acids from human SLC2A3. |
Dilution | WB~~1:2000 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SLC2A3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC2A3 (HGNC:11007) |
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Function | Facilitative glucose transporter (PubMed:26176916, PubMed:32860739, PubMed:9477959). Can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:26176916, PubMed:9477959). Mediates the uptake of glucose, 2- deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:26176916, PubMed:9477959). Does not mediate fructose transport (PubMed:26176916, PubMed:9477959). Required for mesendoderm differentiation (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Perikaryon {ECO:0000250|UniProtKB:Q07647}. Cell projection {ECO:0000250|UniProtKB:Q07647}. Note=Localized to densely spaced patches along neuronal processes. {ECO:0000250|UniProtKB:Q07647} |
Tissue Location | Highly expressed in brain (PubMed:8457197). Expressed in many tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Facilitative glucose transporter. Probably a neuronal glucose transporter.
References
Kayano T.,et al.J. Biol. Chem. 263:15245-15248(1988).
Stuart C.A.,et al.Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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