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NAA40 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - NAA40 Antibody (C-Term) AP22107b
    All lanes : Anti-NAA40 Antibody (C-Term) at 1:2000 dilution Lane 1: human testis lysate Lane 2: mouse stomach lysate Lane 3: mouse spleen lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q86UY6
Other Accession Q8VE10
Reactivity Human, Mouse
Predicted Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 27194 Da
Additional Information
Gene ID 79829
Other Names N-alpha-acetyltransferase 40, 2.3.1.-, N-acetyltransferase 11, NatD catalytic subunit, NAA40, NAT11
Target/Specificity This NAA40 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 179-222 amino acids from the human region of human NAA40.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNAA40 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAA40 {ECO:0000303|PubMed:19660095, ECO:0000312|HGNC:HGNC:25845}
Function N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha- acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level)
Research Areas
Citations (0)
citation

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Background

Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Taylor T.D.,et al.Nature 440:497-500(2006).
Polevoda B.,et al.BMC Proc. 3:S2-S2(2009).
Hole K.,et al.PLoS ONE 6:E24713-E24713(2011).

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$ 365.00
$ 140.00
Cat# AP22107b
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