UPP1 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q16831 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33934 Da |
Gene ID | 7378 |
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Other Names | Uridine phosphorylase 1, UPase 1, UrdPase 1, 2.4.2.3, UPP1, UP |
Target/Specificity | This UPP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 205-237 amino acids from human UPP1. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | UPP1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UPP1 (HGNC:12576) |
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Synonyms | UP |
Function | Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate which can then be utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (PubMed:7488099). Shows broad substrate specificity and can also accept deoxyuridine and other analogous compounds (Probable). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
References
Watanabe S.,et al.Biochem. Biophys. Res. Commun. 216:265-272(1995).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Roosild T.P.,et al.BMC Struct. Biol. 9:14-14(2009).
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