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NUP93 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P-Leica, E |
|---|---|
| Primary Accession | Q8N1F7 |
| Other Accession | A5PJZ5, Q8BJ71, Q66HC5 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 93488 Da |
| Gene ID | 9688 |
|---|---|
| Other Names | Nuclear pore complex protein Nup93, 93 kDa nucleoporin, Nucleoporin Nup93, NUP93, KIAA0095 |
| Target/Specificity | This NUP93 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-54 amino acids from the human NUP93. |
| Dilution | WB~~1:2000 IHC-P-Leica~~1:100 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NUP93 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NUP93 |
|---|---|
| Synonyms | KIAA0095 |
| Function | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540). May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725). |
| Cellular Location | Nucleus membrane {ECO:0000250|UniProtKB:Q66HC5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q66HC5}. Nucleus, nuclear pore complex. Nucleus envelope Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.
References
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Grandi P.,et al.Mol. Biol. Cell 8:2017-2038(1997).
Hase M.E.,et al.Mol. Biol. Cell 14:1923-1940(2003).
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