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> home > Products > Primary Antibodies > Antibody Collections > Ribonucleoprotein > RPL13 Antibody (Center)
RPL13 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P26373 |
| Other Accession | Q56JZ1, Q9Z313, P47963, P41123 |
| Reactivity | Human |
| Predicted | Bovine, Hamster, Mouse, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 24261 Da |
| Gene ID | 6137 |
|---|---|
| Other Names | 60S ribosomal protein L13, Breast basic conserved protein 1, RPL13, BBC1 |
| Target/Specificity | This RPL13 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 49-82 amino acids from the Central region of human RPL13. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RPL13 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RPL13 |
|---|---|
| Synonyms | BBC1 |
| Function | Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:31630789, PubMed:32669547). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (Probable). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (Probable). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (Probable). As part of the LSU, it is probably required for its formation and the maturation of rRNAs (PubMed:31630789). Plays a role in bone development (PubMed:31630789). |
| Cellular Location | Cytoplasm |
| Tissue Location | Higher levels of expression in benign breast lesions than in carcinomas. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Adams S.M.,et al.Hum. Mol. Genet. 1:91-96(1992).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Daub H.,et al.Mol. Cell 31:438-448(2008).
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$ 192.50
$ 75.00
Cat# AP22061c
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