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NT5C Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TCD5 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 23383 Da |
| Gene ID | 30833 |
|---|---|
| Other Names | 5'(3')-deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5', 3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2 |
| Target/Specificity | This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 164-195 amino acids from human NT5C. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NT5C Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NT5C |
|---|---|
| Synonyms | DNT1, UMPH2 |
| Function | Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Detected in skeletal muscle, heart and pancreas. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.
References
Rampazzo C.,et al.J. Biol. Chem. 275:5409-5415(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Rampazzo C.,et al.Gene 294:109-117(2002).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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