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RSL1D1 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O76021 |
| Other Accession | Q5RCE6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 54973 Da |
| Antigen Region | 455-485 aa |
| Gene ID | 26156 |
|---|---|
| Other Names | Ribosomal L1 domain-containing protein 1, CATX-11, Cellular senescence-inhibited gene protein, Protein PBK1, RSL1D1 |
| Target/Specificity | This RSL1D1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 455-485 amino acids from human RSL1D1. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RSL1D1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RSL1D1 |
|---|---|
| Synonyms | CATX11, CSIG {ECO:0000303|PubMed:1867864 |
| Function | Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. |
| Cellular Location | Nucleus, nucleolus. Note=Colocalizes with ING1 in the nucleolus after UV stress. |
| Tissue Location | Expressed at high intensities in the heart, skeletal muscle, and placenta. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
References
Huch G.,et al.Placenta 19:557-567(1998).
Petroziello J.,et al.Oncogene 23:7734-7745(2004).
Guo S.-Z.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
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