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PYGL Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P06737 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 97149 Da |
| Gene ID | 5836 |
|---|---|
| Other Names | Glycogen phosphorylase, liver form, PYGL |
| Target/Specificity | This PYGL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 809-843 amino acids from human PYGL. |
| Dilution | WB~~1:2000 IHC-P~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PYGL Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PYGL (HGNC:9725) |
|---|---|
| Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
| Cellular Location | Cytoplasm, cytosol. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
References
Newgard C.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8132-8136(1986).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Chang S.,et al.Hum. Mol. Genet. 7:865-870(1998).
Burwinkel B.,et al.Am. J. Hum. Genet. 62:785-791(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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