COL11A1 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P12107 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 181065 Da |
Gene ID | 1301 |
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Other Names | Collagen alpha-1(XI) chain, COL11A1, COLL6 |
Target/Specificity | This COL11A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-75 amino acids from human COL11A1. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | COL11A1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | COL11A1 |
---|---|
Synonyms | COLL6 |
Function | May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793} |
Tissue Location | Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon |
Provided below are standard protocols that you may find useful for product applications.
Background
May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
References
Yoshioka H.,et al.J. Biol. Chem. 265:6423-6426(1990).
Annunen S.,et al.Am. J. Hum. Genet. 65:974-983(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Bernard M.,et al.J. Biol. Chem. 263:17159-17166(1988).
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