APOA4 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P06727 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45372 Da |
Gene ID | 337 |
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Other Names | Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4 |
Target/Specificity | This APOA4 antibody is generated from a rabbit immunized with a recombinant protein. |
Dilution | WB~~1:8000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | APOA4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APOA4 |
---|---|
Function | May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
Cellular Location | Secreted. |
Tissue Location | Synthesized primarily in the intestine and secreted in plasma |
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Provided below are standard protocols that you may find useful for product applications.
Background
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
References
Karathanasis S.K.,et al.Biochemistry 25:3962-3970(1986).
Karathanasis S.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8457-8461(1986).
Elshourbagy N.A.,et al.J. Biol. Chem. 262:7973-7981(1987).
Yang C.,et al.Biochim. Biophys. Acta 1002:231-237(1989).
Fullerton S.M.,et al.Hum. Genet. 115:36-56(2004).
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