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Mouse Ptk7 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8BKG3 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 117532 Da |
| Gene ID | 71461 |
|---|---|
| Other Names | Inactive tyrosine-protein kinase 7, Protein chuzhoi, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, Ptk7 |
| Target/Specificity | This Mouse Ptk7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 702-737 amino acids from the C-terminal region of Mouse Ptk7. |
| Dilution | WB~~1:1000-1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Ptk7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Ptk7 |
|---|---|
| Function | Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. |
| Cellular Location | Membrane; Single-pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells |
| Tissue Location | Expressed at high levels in lung and un-pregnant uterus among adult tissues, and in the tail, limbs, somites, gut and craniofacial regions among embryonic tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
References
Jung J.-W.,et al.Gene 328:75-84(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Daigo Y.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Lu X.,et al.Nature 430:93-98(2004).
Gundry R.L.,et al.Mol. Cell. Proteomics 8:2555-2569(2009).
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