Zebrafish ak2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, FC, E |
---|---|
Primary Accession | Q1L8L9 |
Reactivity | Human, Mouse, Zebrafish |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26616 Da |
Antigen Region | 147-183 aa |
Gene ID | 321793 |
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Other Names | Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, ak2 |
Target/Specificity | This Zebrafish ak2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 147-183 amino acids from the Central region of Zebrafish ak2. |
Dilution | WB~~1:2000 IHC-P~~1:25 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Zebrafish ak2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ak2 |
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Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. |
Cellular Location | Mitochondrion intermembrane space {ECO:0000255|HAMAP-Rule:MF_03168} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
References
Howe K.,et al.Nature 496:498-503(2013).
Pannicke U.,et al.Nat. Genet. 41:101-105(2009).
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