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CNP Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P09543 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47579 Da |
| Gene ID | 1267 |
|---|---|
| Other Names | 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase, CNP |
| Target/Specificity | This CNP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 92-126 amino acids from human CNP. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CNP Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CNP (HGNC:2158) |
|---|---|
| Function | Catalyzes the formation of 2'-nucleotide products from 2',3'- cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:P16330}; Lipid- anchor {ECO:0000250|UniProtKB:P16330}. Melanosome. Note=Firmly bound to membrane structures of brain white matter. {ECO:0000250|UniProtKB:P16330} |
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Provided below are standard protocols that you may find useful for product applications.
Background
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
References
Thompson R.J.,et al.Biochem. Soc. Trans. 20:621-626(1992).
Kurihara T.,et al.Biochem. Biophys. Res. Commun. 152:837-842(1988).
Monoh K.,et al.Gene 129:297-301(1993).
Douglas A.J.,et al.Ann. Hum. Genet. 56:243-254(1992).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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