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AKR7L Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NHP1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 36970 Da |
| Antigen Region | 207-237 aa |
| Gene ID | 246181 |
|---|---|
| Other Names | Aflatoxin B1 aldehyde reductase member 4, 1---, AFB1 aldehyde reductase 3, AFB1-AR 3, Aldoketoreductase 7-like, AKR7L, AFAR3, AKR7A4 |
| Target/Specificity | This AKR7L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human AKR7L. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AKR7L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AKR7L |
|---|---|
| Synonyms | AFAR3 {ECO:0000303|PubMed:12879023}, AKR |
| Function | Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity). |
| Tissue Location | Mainly expressed in uterus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).
References
Gregory S.G.,et al.Nature 441:315-321(2006).
Praml C.,et al.Oncogene 22:4765-4773(2003).
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