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FCGR1A Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - FCGR1A Antibody (Center) AP21448c
    All lanes : Anti-FCGR1A Antibody (Center) at 1:8000 dilution Lane 1: HL-60 whole cell lysates Lane 2: THP-1 whole cell lysates Lane 3: human spleen lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • WB - FCGR1A Antibody (Center) AP21448c
    Anti-FCGR1A Antibody (Center)at 1:2000 dilution + NCI-H460 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P12314
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 42632 Da
Additional Information
Gene ID 2209
Other Names High affinity immunoglobulin gamma Fc receptor I, IgG Fc receptor I, Fc-gamma RI, FcRI, Fc-gamma RIA, FcgammaRIa, CD64, FCGR1A, FCG1, FCGR1, IGFR1
Target/Specificity This FCGR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 168-200 amino acids from the Central region of human FCGR1A.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFCGR1A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCGR1A
Synonyms FCG1, FCGR1, IGFR1
Function High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Cellular Location Cell membrane; Single-pass type I membrane protein Note=Stabilized at the cell membrane through interaction with FCER1G
Tissue Location Monocyte/macrophage specific.
Research Areas
Citations (0)
citation

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Background

High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

References

Allen J.M.,et al.Nucleic Acids Res. 16:11824-11824(1988).
Allen J.M.,et al.Science 243:378-381(1989).
Porges A.J.,et al.J. Clin. Invest. 90:2102-2109(1992).
Benech P.D.,et al.J. Exp. Med. 176:1115-1123(1992).
Gregory S.G.,et al.Nature 441:315-321(2006).

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$ 140.00
Cat# AP21448c
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