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DIP2A Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - DIP2A Antibody (Center) AP21444c
    All lanes : Anti-DIP2A Antibody (Center) at 1:1000-1:2000 dilution Lane 1: HL-60 whole cell lysates Lane 2: Hela whole cell lysates Lane 3: Jurkat whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 170 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q14689
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 170369 Da
Additional Information
Gene ID 23181
Other Names Disco-interacting protein 2 homolog A, DIP2 homolog A, DIP2A, C21orf106, DIP2, KIAA0184
Target/Specificity This DIP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 934-969 amino acids from the Central region of human DIP2A.
Dilution WB~~1:1000-1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDIP2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DIP2A
Synonyms C21orf106, DIP2, KIAA0184
Function Catalyzes the de novo synthesis of acetyl-CoA in vitro (By similarity). Promotes acetylation of CTTN, possibly by providing the acetyl donor, ensuring correct dendritic spine morphology and synaptic transmission (By similarity). Binds to follistatin-related protein FSTL1 and may act as a cell surface receptor for FSTL1, contributing to AKT activation and subsequent FSTL1-induced survival and function of endothelial cells and cardiac myocytes (PubMed:20054002).
Cellular Location Cell membrane; Peripheral membrane protein. Mitochondrion {ECO:0000250|UniProtKB:Q8BWT5}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q8BWT5}
Tissue Location Low expression in all tissues tested.
Research Areas
Citations (0)
citation

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Background

May provide positional cues for axon pathfinding and patterning in the central nervous system.

References

Gardiner K.,et al.Genomics 79:833-843(2002).
Tanaka M.,et al.Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hattori M.,et al.Nature 405:311-319(2000).
Nagase T.,et al.DNA Res. 3:17-24(1996).

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$ 365.00
$ 140.00
Cat# AP21444c
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