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DBH Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DBH Antibody (Center) AP21423c
    All lanes : Anti-DBH Antibody (Center) at 1:2000 dilution Lane 1: SH-SY5Y whole cell lysates Lane 2: human plasma lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 69 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P09172
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 69065 Da
Additional Information
Gene ID 1621
Other Names Dopamine beta-hydroxylase, Dopamine beta-monooxygenase, Soluble dopamine beta-hydroxylase, DBH
Target/Specificity This DBH antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-303 amino acids from the Central region of human DBH.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDBH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DBH
Function Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters.
Cellular Location [Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted
Research Areas
Citations (0)
citation

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Background

Conversion of dopamine to noradrenaline.

References

Humphray S.J.,et al.Nature 429:369-374(2004).
Lamouroux A.,et al.EMBO J. 6:3931-3937(1987).
Kobayashi K.,et al.Nucleic Acids Res. 17:1089-1102(1989).
Li B.,et al.Biochem. J. 313:57-64(1996).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).

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$ 140.00
Cat# AP21423c
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