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DBH Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P09172 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 69065 Da |
| Gene ID | 1621 |
|---|---|
| Other Names | Dopamine beta-hydroxylase, Dopamine beta-monooxygenase, Soluble dopamine beta-hydroxylase, DBH |
| Target/Specificity | This DBH antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 270-303 amino acids from the Central region of human DBH. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DBH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DBH |
|---|---|
| Function | Catalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters. |
| Cellular Location | [Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Conversion of dopamine to noradrenaline.
References
Humphray S.J.,et al.Nature 429:369-374(2004).
Lamouroux A.,et al.EMBO J. 6:3931-3937(1987).
Kobayashi K.,et al.Nucleic Acids Res. 17:1089-1102(1989).
Li B.,et al.Biochem. J. 313:57-64(1996).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).
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