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ATP2B3 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF, E |
|---|---|
| Primary Accession | Q16720 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 134197 Da |
| Gene ID | 492 |
|---|---|
| Target/Specificity | This ATP2B3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1161-1194 amino acids from the C-terminal region of human ATP2B3. |
| Dilution | IF~~1:25 WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ATP2B3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ATP2B3 {ECO:0000303|PubMed:8187550, ECO:0000312|HGNC:HGNC:816} |
|---|---|
| Function | ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals (PubMed:18029012, PubMed:22912398, PubMed:25953895, PubMed:27035656). Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment (PubMed:25953895, PubMed:27035656). May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Presynaptic cell membrane {ECO:0000250|UniProtKB:Q64568}; Multi-pass membrane protein. Note=Localized at parallel fiber terminals {ECO:0000250|UniProtKB:Q64568} |
| Tissue Location | Highly expressed in the cerebellum (PubMed:8187550). Expressed in adrenal glands (PubMed:27035656) |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
$ 140.00
Cat# AP21234b
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