(Mouse) Tal1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P22091 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34279 Da |
Gene ID | 21349 |
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Other Names | T-cell acute lymphocytic leukemia protein 1 homolog, TAL-1, Stem cell protein, Tal1, Scl, Tal-1 |
Target/Specificity | This mouse Tal1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 154-188 amino acids from the Central region of mouse Tal1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | (Mouse) Tal1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Tal1 |
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Synonyms | Scl, Tal-1 |
Function | Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:9391090} |
Tissue Location | Erythroid and myeloid cells. |
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Background
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
References
Begley C.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:869-873(1991).
Visvader J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:13707-13712(1997).
Tang T.,et al.J. Biol. Chem. 277:18365-18372(2002).
Goardon N.,et al.EMBO J. 25:357-366(2006).
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