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CXCL11 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O14625 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 10365 Da |
| Gene ID | 6373 |
|---|---|
| Other Names | C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B |
| Target/Specificity | This CXCL11 antibody is generated from a rabbit immunized with a recombinant protein of human CXCL11. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CXCL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CXCL11 |
|---|---|
| Synonyms | ITAC, SCYB11, SCYB9B |
| Function | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. |
| Cellular Location | Secreted. |
| Tissue Location | High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
References
Rani M.R.S.,et al.J. Biol. Chem. 271:22878-22884(1996).
Jacobs K.A.,et al.Gene 198:289-296(1997).
Cole K.E.,et al.J. Exp. Med. 187:2009-2021(1998).
Tensen C.P.,et al.J. Invest. Dermatol. 112:716-722(1999).
Laich A.M.,et al.J. Interferon Cytokine Res. 19:505-513(1999).
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