(Mouse) Eras Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | Q7TN89 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 24321 Da |
Gene ID | 353283 |
---|---|
Other Names | GTPase ERas, E-Ras, Embryonic stem cell-expressed Ras, Eras |
Target/Specificity | This Mouse Eras antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 19-52 amino acids from the N-terminal region of mouse Eras. |
Dilution | WB~~1:1000 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | (Mouse) Eras Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Eras |
---|---|
Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
Tissue Location | Expressed in several undifferentiated mouse embryonic stem cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells.
References
Takahashi K.,et al.Nature 423:541-545(2003).
Carninci P.,et al.Science 309:1559-1563(2005).
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