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CHSY3 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q70JA7 |
| Other Accession | Q5DTK1 |
| Reactivity | Human, Mouse |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100284 Da |
| Gene ID | 337876 |
|---|---|
| Other Names | Chondroitin sulfate synthase 3, Carbohydrate synthase 2, Chondroitin glucuronyltransferase 3, Chondroitin synthase 2, ChSy-2, Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II, N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3, N-acetylgalactosaminyltransferase 3, CHSY3, CHSY2, CSS3 |
| Target/Specificity | This CHSY3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 295-329 amino acids from the Central region of human CHSY3. |
| Dilution | WB~~1:1000-1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHSY3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHSY3 |
|---|---|
| Synonyms | CHSY2, CSS3 |
| Function | Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1. |
| Cellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein |
| Tissue Location | Detected at low levels in brain, cerebral cortex, uterus and small intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity is much reduced compared to CHSY1.
References
Yada T.,et al.J. Biol. Chem. 278:39711-39725(2003).
Kamakari S.,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
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