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DECR1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - DECR1 Antibody (Center) AP21057a
    Western blot analysis of lysates from HepG2 cell line, human heart, human liver, mouse liver, rat liver tissue lysate (from left to right), using DECR1 Antibody (Center)(Cat. #AP21057a). AP21057a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q16698
Other Accession Q64591, Q9CQ62
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 36068 Da
Additional Information
Gene ID 1666
Other Names 4-dienoyl-CoA reductase, mitochondrial, 4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR
Target/Specificity This DECR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 241-274 amino acids from the Central region of human DECR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDECR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DECR1
Synonyms DECR, SDR18C1
Function Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Cellular Location Mitochondrion.
Tissue Location Heart = liver = pancreas > kidney >> skeletal muscle = lung.
Research Areas
Citations (0)
citation

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Background

Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.

References

Koivuranta K.T.,et al.Biochem. J. 304:787-792(1994).
Ding J.H.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
Helander H.M.,et al.Genomics 46:112-119(1997).
Nusbaum C.,et al.Nature 439:331-335(2006).
Choudhary C.,et al.Science 325:834-840(2009).

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$ 365.00
$ 140.00
Cat# AP21057a
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