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Mouse Ror2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - Mouse Ror2 Antibody (C-term) AP20846c
    Western blot analysis of lysates from Hela, SH-SY5Y cell line (from left to right), using Mouse Ror2 Antibody (C-term)(Cat. #AP20846c). AP20846c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
    detail
  • IHC-P - Mouse Ror2 Antibody (C-term) AP20846c
    Immunohistochemical analysis of paraffin-embedded M. stomach section using Mouse Ror2 Antibody (C-term)(Cat#AP20846c). AP20846c was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9Z138
Other Accession Q01974
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 105005 Da
Additional Information
Other Names Tyrosine-protein kinase transmembrane receptor ROR2, mROR2, Neurotrophic tyrosine kinase, receptor-related 2, Ror2
Target/Specificity This Mouse Ror2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 756-790 amino acids from the C-terminal region of human Mouse Ror2.
Dilution WB~~1:1000
IHC-P~~1:25
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Ror2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ror2
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (PubMed:10700181). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
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Background

Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (By similarity).

References

Oishi I.,et al.Genes Cells 4:41-56(1999).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
DeChiara T.M.,et al.Nat. Genet. 24:271-274(2000).
van Wijk N.V.,et al.Biochem. Biophys. Res. Commun. 390:211-216(2009).

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$ 365.00
$ 140.00
Cat# AP20846c
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