HUMAN-UMPS(Y37) Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P11172 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52222 Da |
Gene ID | 7372 |
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Other Names | Uridine 5'-monophosphate synthase, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, Orotidine 5'-phosphate decarboxylase, ODC, OMPdecase, UMPS |
Target/Specificity | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-70 amino acids from human. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HUMAN-UMPS(Y37) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UMPS (HGNC:12563) |
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Function | Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP). |
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Provided below are standard protocols that you may find useful for product applications.
References
Suttle D.P.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1754-1758(1988).
Suchi M.,et al.Adv. Exp. Med. Biol. 253A:511-518(1989).
Suchi M.,et al.Am. J. Hum. Genet. 60:525-539(1997).
Griffith M.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
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