Human-FOSL2 (Y83) Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P15408 |
Other Accession | P51145, P47930 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 35193 Da |
Gene ID | 2355 |
---|---|
Other Names | Fos-related antigen 2, FRA-2, FOSL2, FRA2 |
Target/Specificity | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 70-110 amino acids from human. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Human-FOSL2 (Y83) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FOSL2 |
---|---|
Synonyms | FRA2 |
Function | Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P51145}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Controls osteoclast survival and size (By similarity). As a dimer with JUN, activates LIF transcription (By similarity). Activates CEBPB transcription in PGE2-activated osteoblasts (By similarity).
References
Matsui M.,et al.Oncogene 5:249-255(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
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