ANKRD24 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8TF21 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 124187 Da |
Gene ID | 170961 |
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Other Names | Ankyrin repeat domain-containing protein 24, ANKRD24, KIAA1981 |
Target/Specificity | This ANKRD24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 296-328 amino acids from the Central region of human ANKRD24. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ANKRD24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ANKRD24 (HGNC:29424) |
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Synonyms | KIAA1981 |
Function | Componement of the stereocilia rootlet in hair cells of inner ear. Bridges the apical plasma membrane with the lower rootlet and maintains normal distribution of TRIOBP, thereby reinforcing stereocilia insertion points and organizing rootlets for hearing with long-term resilience. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q80VM7}. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q80VM7} Note=Localizes to hair cell stereocilia rootlets. Concentrated to the stereolocilia insertion point. {ECO:0000250|UniProtKB:Q80VM7} |
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Provided below are standard protocols that you may find useful for product applications.
References
Grimwood J.,et al.Nature 428:529-535(2004).
Nagase T.,et al.DNA Res. 8:319-327(2001).
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