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MT-ND1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P03886 |
| Other Accession | O79874, P03887, O78747 |
| Reactivity | Human |
| Predicted | Bovine, Pig, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35661 Da |
| Gene ID | 4535 |
|---|---|
| Other Names | NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1, MT-ND1, MTND1, NADH1, ND1 |
| Target/Specificity | This MT-ND1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of human MT-ND1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MT-ND1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MT-ND1 |
|---|---|
| Synonyms | MTND1, NADH1, ND1 |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:1959619). Essential for the catalytic activity and assembly of complex I (PubMed:1959619, PubMed:26929434). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03887}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
References
Anderson S.,et al.Nature 290:457-465(1981).
Horai S.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995).
Moilanen J.S.,et al.Mol. Biol. Evol. 20:2132-2142(2003).
Ingman M.,et al.Nature 408:708-713(2000).
Ingman M.,et al.Genome Res. 13:1600-1606(2003).
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