SAMM50 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9Y512 |
Other Accession | Q6AXV4, Q8BGH2 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 51976 Da |
Gene ID | 25813 |
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Other Names | Sorting and assembly machinery component 50 homolog, Transformation-related gene 3 protein, TRG-3, SAMM50, SAM50 |
Target/Specificity | This SAMM50 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 346-380 amino acids from the Central region of human SAMM50. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SAMM50 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SAMM50 |
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Synonyms | SAM50 |
Function | Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes (PubMed:22252321, PubMed:25781180). Required for the assembly of TOMM40 into the TOM complex (PubMed:15644312). |
Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q6AXV4}. Mitochondrion |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be required for the assembly pathway of mitochondrial outer membrane proteins (By similarity).
References
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Kim J.W.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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