CYB5R3 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P00387 |
Other Accession | P20070, P83686, Q9DCN2, Q60HG4, P07514 |
Reactivity | Human, Mouse, Rat |
Predicted | Bovine, Monkey, Pig |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34235 Da |
Gene ID | 1727 |
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Other Names | NADH-cytochrome b5 reductase 3, B5R, Cytochrome b5 reductase, Diaphorase-1, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3 soluble form, CYB5R3, DIA1 |
Target/Specificity | This CYB5R3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 111-144 amino acids from the Central region of human CYB5R3 |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CYB5R3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CYB5R3 (HGNC:2873) |
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Synonyms | DIA1 |
Function | Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor. |
Cellular Location | [Isoform 1]: Endoplasmic reticulum membrane; Lipid-anchor {ECO:0000250|UniProtKB:P20070}; Cytoplasmic side {ECO:0000250|UniProtKB:P20070}. Mitochondrion outer membrane; Lipid-anchor {ECO:0000250|UniProtKB:P20070}; Cytoplasmic side {ECO:0000250|UniProtKB:P20070} |
Tissue Location | [Isoform 2]: Expressed at late stages of erythroid maturation. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
References
Tomatsu S.,et al.Gene 80:353-361(1989).
Voice M.W.,et al.Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
Yoon B.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Lan F.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
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