INHBA Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P08476 |
Other Accession | P18331, P03970, Q04998, P27092, P07995, P43032 |
Reactivity | Human |
Predicted | Bovine, Chicken, Mouse, Pig, Rat, Sheep |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 47442 Da |
Gene ID | 3624 |
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Other Names | Inhibin beta A chain, Activin beta-A chain, Erythroid differentiation protein, EDF, INHBA |
Target/Specificity | This INHBA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 377-410 amino acids from the C-terminal region of human INHBA. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | INHBA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | INHBA |
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Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
References
Mason A.J.,et al.Biochem. Biophys. Res. Commun. 135:957-964(1986).
Murata M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:2434-2438(1988).
Tanimoto K.,et al.DNA Seq. 2:103-110(1991).
Hillier L.W.,et al.Nature 424:157-164(2003).
Stewart A.G.,et al.FEBS Lett. 206:329-334(1986).
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