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GSTT1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GSTT1 Antibody (N-term) AP20614a
    Western blot analysis of lysates from human brain , rat liver and lung tissue lysate (from left to right), using GSTT1 Antibody (N-term)(Cat. #AP20614a). AP20614a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P30711
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 27335 Da
Additional Information
Gene ID 2952
Other Names Glutathione S-transferase theta-1, GST class-theta-1, Glutathione transferase T1-1, GSTT1
Target/Specificity This GSTT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 46-79 amino acids from the N-terminal region of human GSTT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGSTT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSTT1
Function Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2-epoxy- 3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4-nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.
Cellular Location Cytoplasm.
Tissue Location Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in club cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles.
Research Areas
Citations (0)
citation

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Background

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.

References

Pemble S.,et al.Biochem. J. 300:271-276(1994).
Jemth P.,et al.Arch. Biochem. Biophys. 348:247-254(1997).
Sprenger R.,et al.Pharmacogenetics 10:557-565(2000).
Iida A.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.

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$ 182.50
$ 70.00
Cat# AP20614a
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