FXYD6 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, FC, WB, E |
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Primary Accession | Q9H0Q3 |
Other Accession | Q4R566 |
Reactivity | Human, Mouse, Rat |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 10542 Da |
Gene ID | 53826 |
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Other Names | FXYD domain-containing ion transport regulator 6, Phosphohippolin, FXYD6 |
Target/Specificity | This FXYD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-115amino acids from the C-terminal region of human FXYD6. |
Dilution | WB~~1:1000 IHC-P~~1:25 FC~~1:25 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FXYD6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FXYD6 (HGNC:4030) |
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Function | Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Reduces the apparent affinity for intracellular Na(+) with no change in the apparent affinity for extracellular K(+) (PubMed:33231612). In addition to modulating NKA kinetics, may also function as a regulator of NKA localization to the plasma membrane (By similarity). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q91XV6}; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Brandenberger R.,et al.Nat. Biotechnol. 22:707-716(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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