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GSTM4 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q03013 |
| Other Accession | P46439, Q9TSM4, P28161, P04905, Q9TSM5, P09488, Q9N0V4 |
| Reactivity | Human |
| Predicted | Bovine, Monkey, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25561 Da |
| Gene ID | 2948 |
|---|---|
| Other Names | Glutathione S-transferase Mu 4, GST class-mu 4, GST-Mu2, GSTM4-4, GSTM4 |
| Target/Specificity | This GSTM4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from the N-terminal region of human GSTM4. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GSTM4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GSTM4 |
|---|---|
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:8203914, PubMed:8373352). Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 (PubMed:27791009). Can also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (PubMed:27791009). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed in a wide variety of tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Active on 1- chloro-2,4-dinitrobenzene.
References
Comstock K.E.,et al.J. Biol. Chem. 268:16958-16965(1993).
Zhong S.,et al.Biochem. J. 291:41-50(1993).
Ross V.L.,et al.Biochem. J. 294:373-380(1993).
Denson J.,et al.Gene 379:148-155(2006).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
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