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MMAB Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96EY8 |
| Other Accession | Q9D273 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27388 Da |
| Gene ID | 326625 |
|---|---|
| Other Names | Cob(I)yrinic acid a, c-diamide adenosyltransferase, mitochondrial, Cob(I)alamin adenosyltransferase, Methylmalonic aciduria type B protein, MMAB |
| Target/Specificity | This MMAB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 50-81 amino acids from the Central region of human MMAB. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MMAB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MMAB (HGNC:19331) |
|---|---|
| Function | Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191). Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP- binding to MMAB and gated by MMAA (Probable). |
| Cellular Location | Mitochondrion. |
| Tissue Location | Expressed in liver and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Dobson C.M.,et al.Hum. Mol. Genet. 11:3361-3369(2002).
Leal N.A.,et al.J. Biol. Chem. 278:9227-9234(2003).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Schubert H.L.,et al.Biochemistry 45:15188-15196(2006).
Martinez M.A.,et al.Mol. Genet. Metab. 84:317-325(2005).
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