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M Cckar Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - M Cckar Antibody (C-term) AP20509b
    Mouse Cckar Antibody (C-term) (Cat. #AP20509b) western blot analysis in mouse bladder,cerebellum and lung tissue lysates (35ug/lane).This demonstrates the Mouse Cckar antibody detected the Mouse Cckar protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O08786
Other Accession P30551
Reactivity Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 48437 Da
Antigen Region 325-356 aa
Additional Information
Gene ID 12425
Other Names Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R, Cckar
Target/Specificity This Mouse Cckar antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse Cckar.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsM Cckar Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Cckar
Function Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

References

Takata Y., et al. Gene 187:267-271(1997).
Lacourse K.A., et al. Biochem. Biophys. Res. Commun. 236:630-635(1997).
Carninci P., et al. Science 309:1559-1563(2005).

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$ 365.00
$ 140.00
Cat# AP20509b
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