M Tcfap2d Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q91ZK0 |
Other Accession | Q7Z6R9 |
Reactivity | Mouse |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 49548 Da |
Antigen Region | 308-335 aa |
Gene ID | 226896 |
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Other Names | Transcription factor AP-2-delta, AP2-delta, Activating enhancer-binding protein 2-delta, Tfap2d, Tcfap2d |
Target/Specificity | This Mouse Tcfap2d antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of mouse Tcfap2d. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | M Tcfap2d Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Tfap2d |
---|---|
Synonyms | Tcfap2d |
Function | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in both embryonic and newborn brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
References
Zhao F., et al. J. Biol. Chem. 276:40755-40760(2001).
Zhao F., et al. Gene Expr. Patterns 3:213-217(2003).
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