R Ccnl2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q5I0H5 |
Other Accession | Q9JJA7 |
Reactivity | Rat |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 58246 Da |
Antigen Region | 422-450 aa |
Other Names | Cyclin-L2, Ccnl2 |
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Target/Specificity | This RAT Ccnl2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of rat Ccnl2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | R Ccnl2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Ccnl2 |
---|---|
Function | Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. |
Cellular Location | Nucleus speckle {ECO:0000250|UniProtKB:Q96S94}. Nucleus, nucleoplasm {ECO:0000250|UniProtKB:Q96S94} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Also modulates the expression of critical apoptotic factor, leading to cell apoptosis (By similarity).
References
Gibbs R.A., et al. Nature 428:493-521(2004).
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