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SAP30BP Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • IF - SAP30BP Antibody (Center) AP20471c
    Fluorescent image of Hela cells stained with SAP30BP Antibody (Center)(Cat#AP20471C). AP20471C was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
    detail
  • WB - SAP30BP Antibody (Center) AP20471c
    SAP30BP Antibody (Center) (Cat. #AP20471c) western blot analysis in WiDr cell line and human placenta tissue lysates (35ug/lane).This demonstrates the SAP30BP antibody detected the SAP30BP protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IF, WB, E
Primary Accession Q9UHR5
Other Accession Q02614
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 33870 Da
Antigen Region 160-188 aa
Additional Information
Gene ID 29115
Other Names SAP30-binding protein, Transcriptional regulator protein HCNGP, SAP30BP {ECO:0000312|EMBL:AAH075921}
Target/Specificity This SAP30BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the Central region of human SAP30BP.
Dilution IF~~1:25
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSAP30BP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SAP30BP {ECO:0000312|EMBL:AAH07592.1}
Function Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3 (PubMed:21221920). May be involved in the regulation of beta-2- microglobulin genes (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes.

References

Li J.-F., et al. J. Biochem. 136:169-176(2004).
Gou D., et al. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ding J.B., et al. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Hu R.-M., et al. Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Ota T., et al. Nat. Genet. 36:40-45(2004).

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$ 365.00
$ 140.00
Cat# AP20471c
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