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SAP30BP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IF, WB, E |
|---|---|
| Primary Accession | Q9UHR5 |
| Other Accession | Q02614 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33870 Da |
| Antigen Region | 160-188 aa |
| Gene ID | 29115 |
|---|---|
| Other Names | SAP30-binding protein, Transcriptional regulator protein HCNGP, SAP30BP {ECO:0000312|EMBL:AAH075921} |
| Target/Specificity | This SAP30BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-188 amino acids from the Central region of human SAP30BP. |
| Dilution | IF~~1:25 WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SAP30BP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SAP30BP {ECO:0000312|EMBL:AAH07592.1} |
|---|---|
| Function | Plays a role in transcriptional repression by promoting histone deacetylase activity, leading to deacetylation of histone H3 (PubMed:21221920). May be involved in the regulation of beta-2- microglobulin genes (By similarity). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Induces cell death. May act as a transcriptional corepressor of a gene related to cell survival. May be involved in the regulation of beta-2-microglobulin genes.
References
Li J.-F., et al. J. Biochem. 136:169-176(2004).
Gou D., et al. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
Ding J.B., et al. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Hu R.-M., et al. Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Ota T., et al. Nat. Genet. 36:40-45(2004).
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