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PTGER4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P35408 |
| Other Accession | P43114, Q28691, P32240, Q8MJ08 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rabbit, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53119 Da |
| Antigen Region | 242-269 aa |
| Gene ID | 5734 |
|---|---|
| Other Names | Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2 |
| Target/Specificity | This PTGER4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the Central region of human PTGER4. |
| Dilution | WB~~1:1000 IHC-P~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PTGER4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PTGER4 |
|---|---|
| Synonyms | PTGER2 |
| Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
References
Bastien L., et al. J. Biol. Chem. 269:11873-11877(1994).
An S., et al. Biochem. Biophys. Res. Commun. 197:263-270(1993).
Foord S.M., et al. Genomics 35:182-188(1996).
Mori K., et al. J. Mol. Med. 74:333-336(1996).
Kopatz S.A., et al. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
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