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LILRA3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - LILRA3 Antibody (C-term) AP20443b
    LILRA3 Antibody (C-term) (Cat. #AP20443b) western blot analysis in Daudi,HL-60,Raji and Ramos cell line lysates (35ug/lane).This demonstrates the LILRA3 antibody detected the LILRA3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N6C8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 47472 Da
Antigen Region 350-378 aa
Additional Information
Gene ID 11026
Other Names Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31, CD85e, LILRA3, ILT6, LIR4
Target/Specificity This LILRA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human LILRA3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLILRA3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LILRA3
Synonyms ILT6, LIR4
Function Acts as a soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2. Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
Cellular Location Secreted.
Tissue Location Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung
Research Areas
Citations (0)
citation

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Background

May act as soluble receptor for class I MHC antigens.

References

Zhang Z., et al. Protein Sci. 13:2819-2824(2004).
Arm J.P., et al. J. Immunol. 159:2342-2349(1997).
Borges L., et al. J. Immunol. 159:5192-5196(1997).
Norman P.J., et al. Immunogenetics 55:165-171(2003).

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$ 365.00
$ 140.00
Cat# AP20443b
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