SEMA6B Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9H3T3 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 95285 Da |
Antigen Region | 830-859 aa |
Gene ID | 10501 |
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Other Names | Semaphorin-6B, Semaphorin-Z, Sema Z, SEMA6B, SEMAN, SEMAZ |
Target/Specificity | This SEMA6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-859 amino acids from the C-terminal region of human SEMA6B. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SEMA6B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SEMA6B |
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Synonyms | SEMAN, SEMAZ |
Function | Functions as a cell surface repellent for mossy fibers of developing neurons in the hippocampus where it plays a role in axon guidance. May function through the PLXNA4 receptor expressed by mossy cell axons. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in the brain in GABAergic neurons. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May play a role in both peripheral and central nervous system development (By similarity).
References
Kimura T., et al. Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Correa R.G., et al. Genomics 73:343-348(2001).
Clark H.F., et al. Genome Res. 13:2265-2270(2003).
Mural R.J., et al. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Zhang Z., et al. Protein Sci. 13:2819-2824(2004).
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