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POLR2H Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - POLR2H Antibody (Center) AP20263c
    POLR2H Antibody (Center) (Cat. #AP20263c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the POLR2H antibody detected the POLR2H protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P52434
Other Accession Q923G2, NP_006223.2, F2Z4H3
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 17143 Da
Antigen Region 59-87 aa
Additional Information
Gene ID 5437
Other Names DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerases I, II, and III subunit ABC3, DNA-directed RNA polymerase II subunit H, DNA-directed RNA polymerases I, II, and III 171 kDa polypeptide, RPB17, RPB8 homolog, hRPB8, POLR2H
Target/Specificity This POLR2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the Central region of human POLR2H.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOLR2H Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POLR2H (HGNC:9195)
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
Cellular Location Nucleus {ECO:0000269|PubMed:33335104, ECO:0000269|PubMed:9852112, ECO:0000269|Ref.6}. Nucleus, nucleolus
Research Areas
Citations (0)
citation

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Background

This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Kang, X., et al. J. Biol. Chem. 281(26):18216-18226(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)

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$ 182.50
$ 70.00
Cat# AP20263c
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